Gram-Negative Sepsis: Studies in p47 Microvessel Injury Induced by Lung Neutrophil Sequestration and Role of NADPH Oxidase in the Mechanism of
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چکیده
Mice − / − phox and gp91 − / − phox
منابع مشابه
Siglec-E Promotes β2-Integrin-dependent NADPH Oxidase Activation to Suppress Neutrophil Recruitment to the Lung*
Siglec-E is a sialic acid-binding Ig-like lectin expressed on murine myeloid cells. It has recently been shown to function as a negative regulator of β2-integrin-dependent neutrophil recruitment to the lung following exposure to lipopolysaccharide (LPS). Here, we demonstrate that siglec-E promoted neutrophil production of reactive oxygen species (ROS) following CD11b β2-integrin ligation with f...
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